The best way of getting rid of cursed items is to not equip them in first place, but what are you to do if you have a cursed rusty broken spear blocking your autocursing gauntlets of peace, which in turn do not allow you to do anything with your two cursed rings of damage?
- Scrolls of uncursing - an uncursed scroll uncurses one item, a blessed scroll uncurses your whole inventory. These are fairly common, so in difficult situations you might might want to read-identify all the scrolls you have.
- Remove Curse spell - this removes a curse from a single item. It is hard to learn for non-spellcasters, costing 50 PP before modifiers, and 150 PP to book-cast, provided you can hit 100 spell knowledge. You can also learn the spell through a wand of wonder or potion of wonder, though this is highly unlikely.
- Praying - your deity might remove curses from one equipped item. It is a rather costly favor.
Dipping ("!" command) an item in a potion of holy water blesses it. This will not work on items which contain the Essence of Chaos and Corruption, as these will instead transform the potion into a potion of raw chaos. Unluckily, the Bless spell does not work on items.
Blessed scroll of repair
It is possible to move an item's status one step up (cursed to uncursed, uncursed to blessed) by reading a blessed scroll of repair on it. However, only broken items can be targeted by a blessed scroll of repair. So, if your cursed item is not also broken, you must first read a cursed scroll to break it (or find some other way to break it), and then a blessed one to fix it and raise its B/U/C status. This is usually very impractical; by the time you are able to spend two scrolls of repair, one cursed and one blessed, you most likely have access to easier methods of uncursing. However, scrolls of repair can target item stacks of any size, unlike holy water (which has a 19s limit), meaning this method is more resource-efficient as a means of blessing large stacks of items.
Note that as of ADOM 1.2.0 Prerelease 11, scrolls of repair can no longer break normally unbreakable items.
Dipping items into a potion of raw chaos or blessed potion of exchange will change the item into another of its type, removing it from your body. Keep in mind that if you are using raw chaos potions, there is a risk of explosion, which does up to 200 HP of damage and corrupts heavily.
Disarming monsters will gladly help you get rid of any weapon (but not any other kind of wielded item), including cursed ones. The most common ones are ratling fencers and master swordsmen. Some players cycle through their weaponry upon meeting these monsters, thus partially identifying weapons without much risk. The Mad Minstrel has a disarming attack, so in desperate situations you might use him - as long as you can live with losing both the reward of cashing in the weird tome and the chance to perform an ultra ending.
If you are planning to acquire Healing in the chaotic way, the mad doctor will uncurse and remove any helmet you are wearing; it will be dropped at your position and left there when you are teleported at the end of the session. This is a good time to cycle through those leather caps.
Rust monsters can be allowed to rust equipped iron items to dust while standing next to you.
Some monsters with acid or fire attacks can be used to destroy undesired cursed equipment, although this is somewhat risky as this can damage you and more of your equipment and inventory.
Scrolls of item destruction can be employed, but these require at least four items, so if you only have one item to get rid of these only work 25% of the time.
Angering your god might cause item destruction. This is a rather desperate method, usually achieved by just continuously praying until your stuff is destroyed. Unequip anything you don't want to destroy first.
Traps (acid, fireball, ceiling, trick door, exploding runes) can be used to destroy vulnerable stuff by intentionally setting them off. If you have the proper resistances, and/or create the trap in a controlled place, these can be used rather safely. With double acid resistance, an acid trap only does 1 HP damage per activation (although acid resistance also somewhat protects your items from destruction).
Armor with the "trapped" prefix cannot be removed through most normal means of uncursing -- the item must be destroyed or morphed to be removed.
Items which contain the Essence of Chaos and Corruption, such as the Moon Sickle, the Crown of Chaos, and the Medal of Chaos cannot be uncursed using holy water; instead these items will transform the holy water into a potion of raw chaos.
If you are wielding a cursed potion it will shatter upon hitting monster, so in theory you can "weed out" cursed potions that way without getting stuck -- at the cost of losing them, of course.